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Fertility after Chemo- and radiotherapy in children and young adults, FeCT

Fertility can be impaired by radiation and chemotherapy among childhood cancer survivors. Therefore, timely and adequate patient counselling about the risk of infertility and preservation methods is needed. The Borgmann-Staudt group researches and informes on this theme.

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On the following pages you will learn more about the studies and the results concluded by the research group as well as the new international and AWFM guidelines.

For affected persons and their families, various flyers and brochures on the topic of fertility can be downloaded in German and English in the public relations section

Group Leader

Prof. Dr. med. Anja Borgmann-Staudt

Paediatrician

CVK: Campus Virchow-Klinikum

Prof. Dr. med. Anja Borgmann-Staudt

Team

Alumni

Constanze Pfitzer
Constanze Pfitzer
Anne Zynda
Rosa Rendtorff
Simone Reinmuth
Angelina Hohn
Marlies Künzel
Jessica König
Jessica König
Thomas Keil and Cynthia Hohmann
Lutz Goldbeck

2020: Initiating meeting for the multicenter aftercare study

As part of a Germany-wide prospective, multicenter aftercare study "Establishment, Evaluation and Implementation of Multidisciplinary Long-term Aftercare for Adult Survivors of Childhood and Adolescent Cancer", will collect comprehensive data regarding the health situation of former oncological patients. This novel study involves eight university centers (including the Charité); and will be the first of its kind to directly implement findings aimed at improving aftercare structures in Germany.


Press conference 2017

Pressekonferenz

Press conference abstract 16.11.2017

"Giving young cancer patients the chance to have their own children! Why are preventive measures not covered by health insurance?" on November 30, 2017 at the conference center in the Haus der Bundespressekonferenz in Berlin.

 "When the topic of parenthood is included during initial consultation, patients often feel renewed strength in their wish to be cured. Recognizing that they are seen as entire individuals with their own lives, patients and their parents are able to draw hope for the future", pediatric oncologist Anja Borgmann-Staudt, professor at the Charité, opened her presentation as a representative of the GPOH. The press conference was closely related to the publication of the DGHO Health Policy Series Volume 11: Cured of Cancer, but not healthy—No hope for biological children, in which the authors A. Borgmann-Staudt and M. Freund were significantly involved (see photo). For further information, please use the following link to access related news and publications.

 

 


TV reports

The following German language television contributions related to cancer survivors and their wish to have children can be found in the link below: WDR "Aktuelle Stunde" : " Krebs und Kinderwunsch"; TV feature in BR "Kontrovers" with the title: " Kinderwunsch nach Krebs – Krebspatienten ohne Chance auf eigene Kinder " www.br.de/mediathek/video/kinderwunsch-nach-krebs-krebspatienten-ohne-chance-auf-eigene-kinder-av:5a72275de077ff00188170d0


Aftercare award 2015

As a result of the FeCt team’s commitment to studies addressing fertility and procreative fulfillment following oncological therapy during childhood or adolescence, as well as their exemplary work in the area of family-oriented aftercare, the team was the 2015 recipient of the Aftercare Award bestowed by the German Children's Cancer Aftercare Foundation for chronically ill children. (DeutscheKinderKrebsNachsorge-Stifung für das chronisch kranke Kind). ". To learn more about this award, click here: http://www.kinderkrebsnachsorge.de/erleben/nachsorgepreis/preistraeger-2015/


Cooperations

Heike Hölling

The Berlin offspring study is conducted in cooperation with the Robert Koch Institute, in close collaboration with Heike Hölling, study director of the KiGGS study from the Robert Koch Institute. Dipl. Soz. Ralph Schilling is responsible for the documentation and statistical analysis of the data.

Heike Hölling
Heike Hölling

PanCareLIFE

Within the framework of the EU-project PanCareLIFE, the methodical consultation, as well as the documentation and statistical analysis of the data are carried out by Dip.-Soz. Ralph Schilling. The intervention study, which focused on patient education was significantly motivated and shaped by Dr. med. Lutz Goldbeck, Professor of Child and Adolescent Psychiatry in Ulm (deceased on October 30, 2017).

  • The members of the EU-funded PanCareLIFE consortium.

    The members of the EU-funded PanCareLIFE consortium. Image /


Prof. Dr. Ralf Dittrich

The FeCt and PanCareLIFE studies as well as the S2k guideline "Fertility preservation in oncological therapies" were developed in close cooperation with Prof. Dr. Ralf Dittrich, scientific director of Reproductive Medicine in Erlangen. Our current study "Cryopreservation of ovarian tissue and IVM of oocytes from ovarian tissue", relies once again on the expertise of Prof. Dr. Ralf Dittrich.

Prof. Dr. R. Dittrich

Dr. med. Andreas Jantke

The FeCt studies as well as the S1 guideline "Impaired gonadal function after childhood cancer" were carried out in close cooperation with Andreas Jantke, MD, specialist in gynecology and obstetrics with a focus on gynecological endocrinology and reproductive medicine. Our current study "Cryopreservation of ovarian tissue and IVM of oocytes from ovarian tissue", continues to rely on the expertise of Dr. med. Andreas Jantke.

Dr. med. Andreas Jantke

Cryoconservation of ovarian tissue and IVM of oocytes from ovarian tissue

Our project cryoconservation of ovarian tissue and IVM of oocytes from ovarian tissue, enjoys the cooperation of Dr. rer. medic Ina Wilkemeyer from the Clinic for Urology at Charité Mitte. Her experience as head of the cryobank for male germ cells will facilitate the establishment of a laboratory that will also process and preserve female germ cells and ovarian tissue.

Dr. rer. medic. Ina Wilkemeyer
Ina Wilkemeyer

Transition into adult medicine and aftercare consultations

In general, until the age of 18, pediatric oncology patients receive their follow-up care in the Outpatient Clinic/SPC of the Department of Pediatrics with specialists in oncology, hematology, and stem cell transplantation. The MVZ Internal Oncology/Hematology of the Charité offers a continuation of follow-up care to patients 18 years and older. A structured transition to the adult sector, which therefore ensures patients uninterrupted long-term aftercare has only recently been established at the Charité. Prof. Dr. med. Wörmann from the Medical Clinic for Hematology, Oncology and Tumor Immunology and psychologist Wiebke Stritter from the Pediatric Clinic with specialization in oncology and hematology work together with Prof. Anja Borgmann-Staudt to implement this transition into their patient consultations.

Prof. Dr. med. Bernhard Wörmann
Prof. Dr. med. Bernhardt Wörmann
Wiebke Stritter
Wiebke Stritter

Sponsorship

Wer fördert unsere Projekte?

Project

Sponsor

Period of time

   

FeCt-Studien

Kind-Phillip-Stiftung

2006-20012

   

FeCt-Studien

Universitäre Forschungsförderung Charité

2006-2016

   

FeCt-Studien

Deutsche Kinderkrebsstiftung

2008-2010

   

FeCt-Studien

Berliner Krebsgesellschaft

2010-2012

2016

 

FeCt-Studien

Kinderleben e.V.

2012, 2015-2017

   

FeCt-Studien

José Carreras-Leukämiestiftung

2011-2013

   

FeCt-Studien

José Carreras-Leukämiestiftung

2015-2016

   

FeCt-Studien

Kinderhilfe e.V.

2015-2017

   

PanCareLIFE

7. EU Rahmenprogramm

2013-2018

   

FeCt-Studien

Madeleine Schickedanz Kinderkrebsstiftung

2017-2019

   

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